Deep sequencing technology, due to its high throughput and low cost, has become a powerful research tool in a wide range of applications, such as RNA-seq and ChIP-seq.
In the last years there have been many efforts in the bioinformatics community to provide software in R/Bioconductor to simplify the processing and the biological interpretation of such large data sets. However until now, there is no integrated start-to-end analysis solution within R that sufficiently abstracts the technical details and would be suitable for use by biologists. In particular, alignments need to be performed outside of R and genome annotation information must be manually incorporated.
QuasR is a deep sequencing analysis package, a further development of the FMI deep sequencing pipeline, built to make efficient use of available hardware resources and to simplify analysis of next generation sequencing data.
- Developed at FMI - Friedrich Miescher Institute for Biomedical Research
- QuasR is part of the current development version of Bioconductor (2.12) and is scheduled for release with the next Bioconductor release version (2.13) around April 2013.
- The QuasR package has been published at Bioconductor. The QuasR package page, including download links for source and binary formats, are available from: http://www.bioconductor.org/packages/devel/bioc/html/QuasR.html
- https://wiki.systemsx.ch/download/attachments/48925846/bc2_2011_poster_quasr.pdf?version=1&modificationDate=1310456998591 (Poster)